Short Tandem Repeats in Tumours and Immunotherapy

Our July webinar was given by Tugce Bilgin Sonay, from the Department of Computational Biology in the University of Lausanne. In this session, apart from her work, Tugce also explained other studies in this area.

At the beginning of the talk, she gave a general introduction on the detection of short tandem repeats and their impact on phenotype, gene expression and epigenetics. The primary focus of the talk was (1) Microsatellite Instability (MSI) in tumours, which mostly occurs due to the increase in the number of short tandem repeats as a result of a faulty DNA damage repair system, (2) Identification of the effect of the short tandem repeats in these tumours and (3) how these effects can be utilized for immunotherapy.

If you are interested in how short tandem repeats influence cancer and how they can be used for immunotherapy purposes, we strongly suggest you watch this webinar: https://youtu.be/GmjwyTZinjU (unfortunately, this webinar is only available in Turkish)

As ISCB RSG Turkey, we want to thank Tugce again for accepting our invitation and giving this very informative talk!

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RSG-Turkey is a member of The International Society for Computational Biology (ISCB) Student Council (SC) Regional Student Groups (RSG). We are a non-profit community composed of early career researchers interested in computational biology and bioinformatics.

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