Presenter
Özet
The amount of genetic diversity a species possesses is generally thought to result from the accumulation of neutral (selectionally equivalent) mutations. According to the theory of neutral evolution, there should be a linear relationship between heterozygosity (genetic diversity) resulting from the accumulation of neutral mutations by genetic drift and the effective size of populations: as population size increases, the probability of accumulation of neutral mutations increases, and the level of genomic heterozygosity is directly proportional to population size. However, as the analysis of Richard Lewontin, the great evolutionary geneticist of our time, points out for the first time in all clarity, this relationship may be based on an illusion, and many studies point to many species with large population-low genetic variation or low genetic variation large population sizes, and many intraspecific (interpopulation) differences. This contradiction between population size and neutral genetic variation – referred to in the evolutionary biology literature as the Lewontin Paradox – is a challenging problem in evolutionary biology and a subject of active research. In this talk, modern studies and approaches pointing to the solution of Lewontin’s paradox will be summarised in the extended context of the classical Hill-Robertson effect, with emphasis on the process of “linked selection”.
Date: August 8th 2020 – 18:00 (GMT+3)
Language: Turkish
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